【電機系書報討論演講訊息】 

書報討論網頁：http://lms.nthu.edu.tw/course/21140

演講公告網址：/p/403-1175-2629-1.php

題   目：The virtual fruit fly brain -- from bench-top to cyberspace

講   員：羅中泉教授【清大生科院】

時         間：2015年4月10日(星期五) 下午2時20分

                (2:10PM入場，為維持演講品質，2:30PM後不開放入場)

地         點：清華大學台達館105教室

Abstract:

Computer simulations play an important role in testing hypotheses, integrating knowledge and providing predictions of neural circuit functions. While lots efforts have been put into simulating primate or rodent brains, fruit fly (Drosophila melanogaster) is becoming a promising model animal in computational neuroscience for its small brain size, complex cognitive behavior and abundant data from genes to circuits.

With the expectation that most neurons in the Drosophila brain will be mapped out in the next few years, we started the Flysim project with an aim to establish a data-driven neural network model of Drosophila. The project consists of four components: 1) analyzing neuronal data in the Flycircuit database, 2) building a whole-brain spiking neural network model, 3) performing long-term neural network simulations and 4) building a visualization and interactive web interface for the live brian simulations. 

Currently, the Flysim simulator supports the leaky integrate-and-fire neuron model and ionotropic synapses including Ach, AMPA, NMDA and GABAA. We have built a “primitive” Drosophila brain network of ~22,000 neurons, which account for roughly 20% of the fly brain. Despite being at its early stage, this cellular-level brain network model allows us to study some of the fundamental properties of neural networks including balance of excitation and inhibition, critical behavior, long-term stability and plasticity.

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